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Disclosure - Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Property and Equipment (Tables) link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Share-Based Compensation (Tables) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Commitments and Contingencies (Tables) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Unaudited Quarterly Financial Information (Tables) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Organization - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Summary of Significant Accounting Policies - Schedule of Investment Securities (Detail) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Summary of Significant Accounting Policies - Schedule of Fair Value Measurements of Cash Equivalents and Available-for-Sale Investment Securities (Detail) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Summary of Significant Accounting Policies - Common Stock Equivalents Excluded in Calculation of Diluted Loss Per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Property and Equipment - Property and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - Property and Equipment - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - Share-Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 134 - 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Disclosure - Income Taxes - Summary of Gross Unrecognized Tax Benefits (Detail) link:calculationLink link:presentationLink link:definitionLink 142 - Disclosure - Collaborations and License Agreements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 143 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 144 - Disclosure - Commitments and Contingencies - Schedule of Future Minimum Lease Payments having Initial or Remaining Non Cancellable Lease Term (Detail) link:calculationLink link:presentationLink link:definitionLink 145 - Disclosure - Employee Benefit Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 146 - Disclosure - Subsequent Events - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 147 - Disclosure - Unaudited Quarterly Financial Information - Schedule of Quarterly Financial Information (Detail) link:calculationLink link:presentationLink link:definitionLink