101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - Balance Sheets link:calculationLink link:presentationLink link:definitionLink 104 - Statement - Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - Statements of Operations link:calculationLink link:presentationLink link:definitionLink 106 - Statement - Statements of Redeemable Convertible Preferred Stock and Stockholders' Deficit link:calculationLink link:presentationLink link:definitionLink 107 - Statement - Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 108 - Disclosure - Organization link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - Property and Equipment link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - Preferred Stock link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Share-Based Compensation link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Income Taxes link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Collaborations and License Agreements link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Convertible Promissory Notes link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Commitments and Contingencies link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Employee Benefit Plan link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Subsequent Events link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Going Concern link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - Common Stock link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Related Party Transactions link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Property and Equipment (Tables) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Preferred Stock (Tables) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Share-Based Compensation (Tables) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Income Taxes (Tables) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Net (Loss) Income per Common Share (Detail) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Common Stock Equivalents Excluded in Calculation of Diluted (Loss) Earning Per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Property and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 132 - Disclosure - Property and Equipment - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 133 - Disclosure - Preferred Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 134 - Disclosure - Accrued and Unpaid Dividends for Preferred Stock Issuance (Detail) link:calculationLink link:presentationLink link:definitionLink 135 - Disclosure - Share Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 136 - Disclosure - Total Stock-based Compensation Expense (Detail) link:calculationLink link:presentationLink link:definitionLink 137 - Disclosure - Weighted-average Assumptions Used for Calculating Value of Options Granted (Detail) link:calculationLink link:presentationLink link:definitionLink 138 - Disclosure - Stock Options Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 139 - Disclosure - Income Tax Expense(Benefit) (Detail) link:calculationLink link:presentationLink link:definitionLink 140 - Disclosure - Deferred Tax Asset and Liabilities (Detail) link:calculationLink link:presentationLink link:definitionLink 141 - Disclosure - Income Taxes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 142 - Disclosure - Collaborations and License Agreements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 143 - Disclosure - Convertible promissory Notes - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 144 - Disclosure - Commitments and Contingencies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 145 - Disclosure - Employee Benefit Plan - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 146 - Disclosure - Subsequent Event - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 147 - Disclosure - Going Concern - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 148 - Disclosure - Summary of Effective Income Tax Rate (Detail) link:calculationLink link:presentationLink link:definitionLink 149 - Disclosure - Common Stock - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 150 - Disclosure - Related Party Transactions - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink