101 - Document - Document and Entity Information link:calculationLink link:presentationLink link:definitionLink 103 - Statement - Condensed Consolidated Balance Sheets link:calculationLink link:presentationLink link:definitionLink 104 - Statement - Condensed Consolidated Balance Sheets (Parenthetical) link:calculationLink link:presentationLink link:definitionLink 105 - Statement - Condensed Consolidated Statements of Operations link:calculationLink link:presentationLink link:definitionLink 106 - Statement - Condensed Consolidated Statements of Comprehensive Loss link:calculationLink link:presentationLink link:definitionLink 107 - Statement - Condensed Consolidated Statements of Cash Flows link:calculationLink link:presentationLink link:definitionLink 108 - Disclosure - Organization link:calculationLink link:presentationLink link:definitionLink 109 - Disclosure - Summary of Significant Accounting Policies link:calculationLink link:presentationLink link:definitionLink 110 - Disclosure - Property and Equipment link:calculationLink link:presentationLink link:definitionLink 111 - Disclosure - Share-Based Compensation link:calculationLink link:presentationLink link:definitionLink 112 - Disclosure - Collaborations and License Agreements link:calculationLink link:presentationLink link:definitionLink 113 - Disclosure - Summary of Significant Accounting Policies (Policies) link:calculationLink link:presentationLink link:definitionLink 114 - Disclosure - Summary of Significant Accounting Policies (Tables) link:calculationLink link:presentationLink link:definitionLink 115 - Disclosure - Property and Equipment (Tables) link:calculationLink link:presentationLink link:definitionLink 116 - Disclosure - Share-Based Compensation (Tables) link:calculationLink link:presentationLink link:definitionLink 117 - Disclosure - Organization - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 118 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 119 - Disclosure - Summary of Significant Accounting Policies - Schedule of Investment Securities (Detail) link:calculationLink link:presentationLink link:definitionLink 120 - Disclosure - Summary of Significant Accounting Policies - Schedule of Investment Securities (Parenthetical) (Detail) link:calculationLink link:presentationLink link:definitionLink 121 - Disclosure - Summary of Significant Accounting Policies - Schedule of Fair Value Measurements of Cash Equivalents and Available-for-Sale Investment Securities (Detail) link:calculationLink link:presentationLink link:definitionLink 122 - Disclosure - Summary of Significant Accounting Policies - Common Stock Equivalents Excluded in Calculation of Diluted Loss Per Share (Detail) link:calculationLink link:presentationLink link:definitionLink 123 - Disclosure - Property and Equipment - Property and Equipment (Detail) link:calculationLink link:presentationLink link:definitionLink 124 - Disclosure - Property and Equipment - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 125 - Disclosure - Share-Based Compensation - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink 126 - Disclosure - Share-Based Compensation - Total Stock-Based Compensation Expense (Detail) link:calculationLink link:presentationLink link:definitionLink 127 - Disclosure - Share-Based Compensation - Weighted-Average Assumptions Used for Calculating Value of Options Granted (Detail) link:calculationLink link:presentationLink link:definitionLink 128 - Disclosure - Share-Based Compensation - Stock Options Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 129 - Disclosure - Share-Based Compensation - Summary of Information Regarding Time Based RSU Activity (Detail) link:calculationLink link:presentationLink link:definitionLink 130 - Disclosure - Share-Based Compensation - Summary of Information Regarding Milestone RSU grants and TSR RSU grants (Detail) link:calculationLink link:presentationLink link:definitionLink 131 - Disclosure - Collaborations and License Agreements - Additional Information (Detail) link:calculationLink link:presentationLink link:definitionLink