STOCK INFORMATION

Shareholder Breakdown

Shareholder	Holders	Value ($MM)	% O/S	Shares
Institution	182	346.80	83.27	46,001,153
Mutual Fund	328	203.10	41.88	23,105,646
Insider	11	28.38	4.93	2,718,097

Institutional Shareholder Rotation

Shareholder	Holders	Value Chg ($MM)	% O/S	Share Change
Buyers	89	66.76	15.97	8,822,770
Sellers	92	-54.94	12.51	-6,914,339
Net		11.83	3.45	1,908,431

Institutional Shareholder Concentration

	Value ($MM)	% O/S	Shares
Total Inst.	392.50	90.35	49,910,406
Top 10 Inst.	236.33	55.62	30,728,628
Top 20 Inst.	314.09	72.50	40,049,695
Top 50 Inst.	367.44	84.74	46,808,138

Institutional Shareholder Style

	Holders	Value ($MM)	% Inst Shares	Shares
Growth	45	51.89	12.40	6,851,822
Aggressive Growth	4	2.08	0.50	278,679
Core Growth	33	26.85	6.33	3,498,844
Growth	8	22.97	5.56	3,074,299
Income	3	0.99	0.24	130,218
Income Value	2	0.91	0.22	122,164
Yield	1	0.08	0.01	8,054
Index	25	81.44	19.72	10,894,446
Other	66	198.34	48.03	26,528,154
Broker Dealer	15	6.45	1.56	863,872
GARP	23	111.58	27.03	14,931,426
Hedge Fund	26	45.14	10.90	6,023,736
Specialty	1	0.27	0.06	35,850
VC Private Equity	1	34.91	8.47	4,673,270
Value	18	8.59	1.75	968,447
Core Value	14	6.60	1.28	709,344
Deep Value	4	1.99	0.47	259,103

Top Holders: Institutional Investor

Holder	Shares Held	% O/S	Share Change	Filing Date
Fidelity Management & Research Company	6,126,993	11.09	-2,143,200	9/30/19
Alafi Capital Company, LLC	4,673,270	8.47	720,000	9/10/19
The Vanguard Group, Inc.	4,182,130	7.57	-8,051	9/30/19
Wasatch Global Investors Inc	4,015,760	7.27	1,667,728	9/30/19
BlackRock Institutional Trust Company, N.A.	3,526,463	6.38	64,516	9/30/19
Bellevue Asset Management AG	2,588,990	4.69	343,490	9/30/19
Dimensional Fund Advisors, L.P.	1,758,347	3.18	48,847	9/30/19
Schroder Investment Management North America Inc.	1,428,551	2.59	-1,918	9/30/19
Millennium Management LLC	1,236,968	2.24	1,101,616	9/30/19
Alexandria Venture Investments LLC	1,191,156	2.16	--	4/15/19
Samlyn Capital, LLC	1,179,683	2.13	147,578	9/30/19
State Street Global Advisors (US)	1,157,047	2.09	157,947	9/30/19
Mates (Sharon)	1,138,707	2.06	--	4/15/19
Alafi (Christopher D)	1,015,800	1.84	160,824	9/30/19
Candriam Luxembourg S.A.	918,000	1.66	400,000	9/30/19
Candriam Belgium S.A.	918,000	1.66	--	10/31/19
Rhenman & Partners Asset Management AB	850,000	1.54	-99,833	9/30/19
ClearBridge Investments, LLC	785,138	1.42	777,317	9/30/19
Citadel LLC	706,321	1.28	366,673	9/30/19
Geode Capital Management, L.L.C.	652,371	1.18	7,957	9/30/19
Point72 Asset Management, L.P.	559,900	1.01	559,900	9/30/19
Northern Trust Investments, Inc.	537,714	0.97	19,253	9/30/19
Morgan Stanley Smith Barney LLC	450,679	0.82	63	9/30/19
Morgan Stanley & Co. LLC	346,872	0.63	336,019	9/30/19
General American Investors Company, Inc.	341,527	0.62	41,585	9/30/19
Two Sigma Investments, LP	337,787	0.61	-53,873	9/30/19
Norges Bank Investment Management (NBIM)	330,070	0.60	--	12/31/18
Charles Schwab Investment Management, Inc.	273,955	0.50	2,675	9/30/19
Riggs (Rory B)	270,975	0.49	1,941	9/30/19
Nuveen LLC	241,611	0.44	-376,643	9/30/19
D. E. Shaw & Co., L.P.	229,526	0.42	-125,362	9/30/19
Jacobs Levy Equity Management, Inc.	208,627	0.38	81,243	9/30/19
AXA Rosenberg Investment Management LLC	202,011	0.37	69,500	9/30/19
BlackRock Financial Management, Inc.	201,676	0.37	11,175	9/30/19
BlackRock Investment Management, LLC	192,105	0.35	40,806	9/30/19
JP Morgan Asset Management	176,625	0.32	-675	9/30/19
Deutsche Asset Management Americas	175,719	0.32	-55,655	9/30/19
Opaleye Management Inc.	170,000	0.31	170,000	9/30/19
Squarepoint Capital LLP	147,257	0.27	93,712	9/30/19
Pictet Asset Management Ltd.	146,024	0.26	8,500	9/30/19
A.R.T. Advisors, LLC	143,921	0.26	110,700	9/30/19
Nexthera Capital LP	143,665	0.26	143,665	6/30/19
PDT Partners, LLC	129,741	0.23	84,537	9/30/19
Schroder Investment Management Ltd. (SIM)	129,103	0.23	--	10/31/19
Jefferies LLC	120,399	0.22	113,387	9/30/19
Verition Fund Management LLC	118,091	0.21	118,091	9/30/19
Ohio Public Employees Retirement System	112,655	0.20	41,393	9/30/19
BNY Mellon Asset Management	110,665	0.20	-14,256	9/30/19
Pura Vida Investments, LLC	109,130	0.20	109,130	9/30/19
Marcus (Joel S)	100,413	0.18	--	5/31/19