Overview

Intra-Cellular Therapies is a biopharmaceutical company focused on the discovery and clinical development of innovative, small molecule drugs that address underserved medical needs in neuropsychiatric and neurological disorders by targeting intracellular signaling mechanisms within the central nervous system, or CNS. The Company is developing its lead drug candidate, ITI-007, for the treatment of schizophrenia, behavioral disturbances in dementia, bipolar disorder and other neuropsychiatric and neurological disorders.

ITI-007 is in Phase 3 clinical trials as a first-in-class treatment for schizophrenia. Current medications available for the treatment of schizophrenia do not adequately address the broad array of symptoms associated with this CNS disorder. In addition, use of these current medications is limited by their substantial side effects. ITI-007 is designed to be effective across a wider range of symptoms, treating both the acute and residual phases of schizophrenia, with improved safety and tolerability.

The Company is also utilizing its phosphodiesterase platform and other proprietary chemistry platforms to develop drugs for the treatment of several neuropsychiatric and neurodegenerative diseases. The lead compound in this platform, ITI-214, has finished several Phase 1 clinical trials and has been demonstrated to be safe and well-tolerated.  In addition, the Company is developing inhibitors against other targets for CNS indications such as Alzheimer's disease, Parkinson's disease and depression and non-CNS indications such as pulmonary arterial hypertension, multiple sclerosis, COPD and lung fibrosis.

We have assembled a management team with significant industry experience to lead the discovery and development of our product candidates. We complement our management team with a group of scientific and clinical advisors that includes recognized experts in the fields of schizophrenia and other central nervous system disorders including Nobel Laureate, Dr. Paul Greengard, one of our co-founders.


NASDAQ: ITCI
$ 42.35 +0.83 (2.00%)
Day High: 42.40
Day Low:  40.70
Volume:    2,049,781
4:00 PM ET
Sep 28, 2016

Delayed ~20 min., by eSignal.